There are four types of guidelines that can appear in FotoFusion:

The Safe and Bleed areas are regions used to lay printed material out with precision. These features are available in the ENHANCED and EXTREME versions of FotoFusion.

Safe Area
Safe inset will create guidelines inside the canvas area, to indicate the area of the canvas will be guaranteed to be visible after the layout is printed, cropped and/or bound.

If you perform an AutoCollage on a page with a safe inset, the resulting arrangement of images will be contained within the interior portion of the safe zone.

You can manually position images over the safe zone. Images will snap to the guidelines for your convenience.

An example to illustrate the safe area:
Suppose that you are building a 5" x 7" collage to be placed in an album. The album will hold the picture with a slightly overlapped edge, which may cover 1/4" on each side of the image; the central 4.5" x 6.5" of the collage are what will be visible through the hole in the album sheet.

The "Safe" area insets the size of the photo to take this into account. The Safe area is indicated by margin lines drawn over the collage, to indicate where the edges of the visible part of the collage will be. The printed collage will still be cut at 5" x 7", but tools such as AutoCollage will respect the 'safe' area, and not place any images outside of this bordered area.

Bleed Area
Adding a bleed zone will increase the size of your canvas to give your printed documents room to be trimmed. This feature is usually applied at the request of a professional printing lab.

An example of using a bleed area:
Consider designing a blue 3" x 1.5" business card. If you create a blue rectangle that is exactly 3" x 1.5" across, and print it on a regular sheet of paper, you will need to be extremely careful when cutting the card out to ensure that you cut exactly the right amount of background paper away. Too little and the card will have a white border, too much and you will cut into the card.

The "Bleed" area expands the size of the card to, say, 3.5" x 2" - giving you an extra 1/4" of blue border on each side, plus crop marks to tell you exactly where to cut (along the "trim lines", at 3" x 1.5"). Now you can't miss when cutting the card out - if you are a bit too small or too large, the card will still have a perfect blue edge.

To create a Bleed area, open the Canvas Size dialogue box. Alter the values in the Printing Zone, resetting the "Bleed: Inflate by... " to a suitable amount. The first option allows you to apply a uniform value on all four sides. The next four options allow you to assign separate values for the gutter, edge, top and bottom sides.
 

Canvas Grid
 
To add a grid to help you position your layout, click on TOOLS on the menu, then Canvas, and select GRID SETTINGS.

Snap to Grid: checkmark to turn on a "magnetic" effect when moving or resizing your frames. The white snap lines will gravitate towards the grid's units of measure.
Display Grid Lines: checkmark to make a grid appear on your canvas
The RGB values allow you to change the color of the grid lines.
Change the Horizontal and Vertical values (eg. 0.5") to change the spacing of the grid. Hit OK to apply.

To turn off the grid, repeat the steps above and uncheck the SNAP TO GRID or DISPLAY GRID LINES checkbox(es).

You can make any type of grid you would like, such as setting up a page suitable for column or rows, particularly to use with text.
 
If there is a particular grid setup that you will need to use repeatedly, you can make a preset.

Center Guide
Extreme users will find that any canvases wider than 4:3 will automatically have a guideline drawn down their center.
Select "album two page spread" from the drop-box next to the canvas dimensions to specifically specify the format.

This shows you where the crease in the center of a flush-mount digital wedding album will appear, a particularly useful feature if you are creating double-page spreads.